Faculty Mentoring Undergrads

Design Thinking / Empathic Design

The interdisciplinary aspects of urban regeneration strategies, place making, and urban ecologies.

The history and digital analysis of Norman architecture in England, France and Italy.

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

Epigenetic and genetic mechanisms underlying metabolic disease

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Innate immunity, chronic disease, host-parasite interactions

Super-resolution fluorescence imaging of bacterial cells

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

Molecular mechanisms controlling insulin signaling and fat synthesis.

Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation (phase separation)

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

Statistical Genetics, Genetic Epidemiology, Biostatistics, Network analysis

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Obesity and Aging

Transcriptional Silencing and Aging in Yeast

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

The Cause and Consequence of Somatic Mosaicism in Neurons

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

Molecular embryology--gene regulation in cells committed to specific developmental lineages

The role of glia in the development, maintenance and regeneration of the nervous system

Statistical Genetics, Genetic Epidemiology, Biostatistics, Network analysis

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Obesity and Aging

Genomics, Molecular Evolution, Algorithm Design and Analysis

Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Epigenetic and genetic mechanisms underlying metabolic disease

Cellular and molecular mechanisms of morphogenesis

Developing novel neuroprotection strategies to preserve vision in glaucoma

Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates

Matrix Biology and Engineering

Systems Genetics Approaches to Understand Cardiometabolic Traits

Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

Diagnostic ultrasound - image processing, quantification Molecular imaging using ultrasound Catheter-based ultrasound Ultrasound-based drug/gene delivery Ultrasound image guided therapy

Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy

Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Super-resolution fluorescence imaging of bacterial cells

Diagnostic ultrasound - image processing, quantification Molecular imaging using ultrasound Catheter-based ultrasound Ultrasound-based drug/gene delivery Ultrasound image guided therapy

Architecture and function of biological membranes

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Design, Development and Optimization of Medical Imaging Technologies

Epigenetic and genetic mechanisms underlying metabolic disease

Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment

Innate immunity, chronic disease, host-parasite interactions

Molecular Mechanics of Muscle Contraction and Cell Movement

Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry

Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

The Cause and Consequence of Somatic Mosaicism in Neurons

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

Neural Circuits in Healthy and Diseased Brains

Regulation of gene expression during lymphocyte development

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.<br> Cell Biology of bacterial pathogenesis. <br>The innate immune response to bacterial infection.

Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders

Signal transduction in cancer cells

Regeneration and Systemic Responses to Tissue Damage

Photoacoustic imaging, light microscopy, neuroscience, cardiovascular biology, cancer, regenerative medicine

The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases

Regulation and function of tyrosine phosphorylation in complex networks

Genomics, Molecular Evolution, Algorithm Design and Analysis

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Tailored fit targeting approaches: Cancer Immunotherapy, Antibodies and conjugates

Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.

Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

Molecular mechanisms controlling insulin signaling and fat synthesis.

Translating our discoveries in the microcirculation to tangible benefits in patients.

Understanding mechanisms of ischemia-reperfusion (IR) injury after lung transplantation such as vascular inflammation, diagnosis via molecular imaging, and identifying therapeutic targets for the prevention or treatment of IR injury.

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension

Matrix Biology and Engineering

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.<br> Cell Biology of bacterial pathogenesis. <br>The innate immune response to bacterial infection.

Cell signaling of protein kinases in development and disease

Architecture and function of biological membranes

Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense

Obesity and Aging

Chromosome segregation and aneuploidy in meiosis and mitosis

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.

Regeneration and Systemic Responses to Tissue Damage

Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Structure and Dynamics in Supercritical Fluids. Quantum and Semiclassical Many-Body Dynamics

Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry

Energy-relevant catalysis, particularly at the interface of molecular electrochemistry and materials

Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

The Cause and Consequence of Somatic Mosaicism in Neurons

Regulation and function of tyrosine phosphorylation in complex networks

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Computer architecture, application-specific accelerators, temperature-aware and power-aware computing

Communication through non-standard modalities

Land-atmosphere interaction; climate-vegetation modeling; and catchment hydrology

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

Systems Genetics Approaches to Understand Cardiometabolic Traits

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation (phase separation)

The Cause and Consequence of Somatic Mosaicism in Neurons

Transcriptional Silencing and Aging in Yeast

Matrix Biology and Engineering

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.<br> Cell Biology of bacterial pathogenesis. <br>The innate immune response to bacterial infection.

Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism

Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

Molecular embryology--gene regulation in cells committed to specific developmental lineages

Regeneration and Systemic Responses to Tissue Damage

The role of glia in the development, maintenance and regeneration of the nervous system

Statistical Genetics, Genetic Epidemiology, Biostatistics, Network analysis

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates

Cellular and genetic determinants of atherosclerosis and restenosis.

Transcriptional Silencing and Aging in Yeast

Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine

Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics

Regulation of gene expression during lymphocyte development

Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

Herpes Simplex Virus Infection of Neurons

Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

Innate immunity, chronic disease, host-parasite interactions

Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry

Understanding mechanisms of ischemia-reperfusion (IR) injury after lung transplantation such as vascular inflammation, diagnosis via molecular imaging, and identifying therapeutic targets for the prevention or treatment of IR injury.

Epidemiology, microbiology and immunology of enteric pathogens.

Cellular and molecular mechanisms of allergic disease in humans.

Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.

Regulation of gene expression during lymphocyte development

Soft Matter Polymer Science Biophysics Biofilms

Herpes Simplex Virus Infection of Neurons

Molecular Mechanics of Muscle Contraction and Cell Movement

Immune mechanisms of defense against enteric (diarrheal) infections

Soft Matter Polymer Science Biophysics Biofilms

Additive Manufacturing, Multifunctional Materials, Tailored Materials, Orthopaedic Implants

Soft Matter Polymer Science Biophysics Biofilms

Additive Manufacturing, Multifunctional Materials, Tailored Materials, Orthopaedic Implants

Human intestinal parasitology

Epigenetic and genetic mechanisms underlying metabolic disease

Innate immunity, chronic disease, host-parasite interactions

Molecular mechanisms controlling insulin signaling and fat synthesis.

Photoacoustic imaging, light microscopy, neuroscience, cardiovascular biology, cancer, regenerative medicine

Regulation of stem cell function and tumorigenesis by epigenetics and biomolecular condensation (phase separation)

Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense

Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates

Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness

Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

Herpes Simplex Virus Infection of Neurons

Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders

Super-resolution fluorescence imaging of bacterial cells

HIV diversity, evolution, fitness, drug resistance and disease progression

Regulation of gene expression during lymphocyte development

Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

Innate immunity, chronic disease, host-parasite interactions

HIV diversity, evolution, fitness, drug resistance and disease progression

Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment

Super-resolution fluorescence imaging of bacterial cells

Signal transduction in cancer cells

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

Molecular mechanisms controlling insulin signaling and fat synthesis.

Cellular and molecular mechanisms of morphogenesis

Understanding mechanisms of ischemia-reperfusion (IR) injury after lung transplantation such as vascular inflammation, diagnosis via molecular imaging, and identifying therapeutic targets for the prevention or treatment of IR injury.

The Cause and Consequence of Somatic Mosaicism in Neurons

Regulation and function of tyrosine phosphorylation in complex networks

Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Tailored fit targeting approaches: Cancer Immunotherapy, Antibodies and conjugates

Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.

Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Molecular mechanisms controlling insulin signaling and fat synthesis.

Translating our discoveries in the microcirculation to tangible benefits in patients.

The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Translating our discoveries in the microcirculation to tangible benefits in patients.

Chromosome segregation and aneuploidy in meiosis and mitosis

Herpes Simplex Virus Infection of Neurons

The role of glia in the development, maintenance and regeneration of the nervous system

Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates

Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness

Herpes Simplex Virus Infection of Neurons

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Neuroscience

Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer

Regeneration and Systemic Responses to Tissue Damage

Pathophysiology of Status Epilepticus; Mechanisms and pathways of seizure spread

The role of glia in the development, maintenance and regeneration of the nervous system

Developing novel neuroprotection strategies to preserve vision in glaucoma

Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates

Regulation of neural stem cell proliferation during development and adulthood

Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine

Studies of various aspects of learning, memory, olfactory discrimination and explosive detection. We develop computer driven learning programs that produce optimal olfactory discrimination and detection learning in rodents.

Neural Circuits in Healthy and Diseased Brains

Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Cell signaling of protein kinases in development and disease

The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases

Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

Translating our discoveries in the microcirculation to tangible benefits in patients.

Understanding mechanisms of ischemia-reperfusion (IR) injury after lung transplantation such as vascular inflammation, diagnosis via molecular imaging, and identifying therapeutic targets for the prevention or treatment of IR injury.

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension

Morality and ethical behavior Responses to injustice Social exchange and prosocial behavior

Dynamical Systems Analysis of Behavioral Data; Interpersonal Coordination; Postural Control

The effects of emotional experience on cognitive performance and behavior, including the role of emotion in art and other aesthetic experiences.

goal pursuit and motivation; social judgment; behavioral decision making; cooperation and competition

Brain processes that underpin social interaction and cognition during infancy

Auditory, visual, and cross-modal perception, psychology of art, the structure of lives, and the philosophy of mind.

Culture, social ecology, and well-being.

Psychological phenomena related to diversity

The ontogenetic emergence of the moral emotions, cognitions, and behaviors that make children successful cooperators

Affective forecasting, self-knowledge, social cognition, self-reflection, social psychological interventions

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

goal pursuit and motivation; social judgment; behavioral decision making; cooperation and competition

Cellular and genetic determinants of atherosclerosis and restenosis.

Epigenetic Silencing Mechanisms-Implications in Breast Cancer and Rett Syndrome

Epigenetic and genetic mechanisms underlying metabolic disease

Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment

Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders

Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry

Translating our discoveries in the microcirculation to tangible benefits in patients.

The role of glia in the development, maintenance and regeneration of the nervous system

Role of Prosecretory Mitogen 'Lacritin' in Epithelial Homeostasis, Secretion and Innate Defense

Chemical biology of sphingosine 1-phosphate

Modulation of sodium channel gating by beta subunits and novel sodium channel blockers; Synaptic transmission in dorsal horn neurons

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Design, Development and Optimization of Medical Imaging Technologies