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Petri, William

William Petri

Primary Appointment

Medicine- Infectious Diseases and International Health

Contact Information

Division of Infectious Diseases
Charlottesville, VA 22908
Telephone: 434-924-5621
Fax: 434-924-0075
Email: wap3g@virginia.edu

Research Interests

Immune mechanisms of defense against enteric (diarrheal) infections

Research Description

William A. Petri, Jr., M.D., Ph.D. studies immunology and molecular pathogenesis of enteric infections and their consequences. The scope of research includes molecular parasitology of Entamoeba, innate immune host defense against Clostridium difficile, and in Bangladesh acquired immunity to Cryptosporidium. We study infections in mouse models, in humans (including clinical trials) and at the lab bench. AMEBIASIS: Focusing on amebic colitis, his lab identified the Gal/GalNAc-binding lectin of the parasite Entamoeba histolytica that mediates contact-dependent killing of host cells. Cell biologic studies of adherence, apoptosis and endocytosis of human cells by the parasite are active areas of investigation. This work is supported by an R01 to Dr. Petri from the NIH. DNA transformation of the parasite was pioneered in the lab, and is used to study molecular pathogenesis. Clinically, the group has developed FDA-approved antigen-detection tests that allow sensitive and specific diagnosis of amebiasis. Current work is focused on the mechanism of Entamoeba killing of host cells by a unique process called trogocytosis (Ralston KD et al, Nature (2014) 508:526) and the development of an amebiasis vaccine in partnership with the Infectious Diseases Research Institute of Seattle (Abhyankar M et al. Vaccine 35 (2017) 916). C. DIFFICILE: The innate immune response to Clostridium difficile colitis is a new area of investigation. Also supported by a separate R01 to Dr. Petri from the NIH, his lab has discovered that eosinophils protect from C. difficile in both mice (Buonomo EL et al., Cell Reports 2016, 16:1-12) and humans (Kulaylat AS et al., JAMA Surg. doi:10.1001/jamasurg.2018.3174.) Understanding how eosinophils protect, and why inflammasome activation by toxin activation of TLR2 causes death (Cowardin CA et al. Nature Microbiology 2016, doi:10.1038/nmicrobiol.2016.108) are current ares of focus. CRYPTOSPORIDIOSIS: The acquired immune response to Cryptosporidium hominis in children growing up in the urban slums of Bangladesh is a third area of investigation. Supported by another NIH R01 grant, the focus of this research is the role of mucosal immunity in defense, including identification of parasite proteins recognized by IgA and by immune T cells (Steiner KL et al Clin Infect Dis. 2018 Apr 20. doi: 10.1093/cid/ciy310). 19 graduate students have received the PhD degree under Dr. Petri?s mentorship all of whom continue in science, and 25 postdoctoral fellows. Eleven graduates of the lab have received K career development awards from the NIH, and nine have received their own independent R01. Currently there are five graduate students three postdoctoral fellows and 6 faculty conducting research in the Petri group.

Selected Publications

Moreau GB, Ramakrishnan G, Cook HL, Fox TE, Nayak U, Ma JZ, Colgate ER, Kirkpatrick BD, Haque R, Petri WA, Childhood growth and neurocognition are associated with distinct sets of metabolites., 2019; EBioMedicine. () PMID: 31133540 |

Steiner KL, Kabir M, Priest JW, Hossain B, Gilchrist CA, Cook H, Ma JZ, Korpe PS, Ahmed T, Faruque ASG, Haque R, Petri WA, Fecal IgA against a sporozoite antigen at 12 months is associated with delayed time to subsequent cryptosporidiosis in urban Bangladesh: a prospective cohort study., 2019; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. () PMID: 31131855 |

Richard SA, McCormick BJJ, Murray-Kolb LE, Lee GO, Seidman JC, Mahfuz M, Ahmed T, Guerrant RL, Petri WA, Rogawski ET, Houpt E, Kang G, Mduma E, Kosek MN, Lima AAM, Shrestha SK, Chandyo RK, Bhutta Z, Bessong P, Caulfield LE, Enteric dysfunction and other factors associated with attained size at 5?years: MAL-ED birth cohort study findings., 2019; The American journal of clinical nutrition. () PMID: 31127812 |

Berens AE, Kumar S, Tofail F, Jensen SEK, Alam M, Haque R, Kakon SH, Petri WA, Nelson CA, Cumulative psychosocial risk and early child development: validation and use of the Childhood Psychosocial Adversity Scale in global health research., 2019; Pediatric research. () PMID: 31103019 |

Jensen SKG, Tofail F, Haque R, Petri WA, Nelson CA, Child development in the context of biological and psychosocial hazards among poor families in Bangladesh., 2019; PloS one. 14(5) e0215304 PMID: 31059509 |

Perdue KL, Jensen SKG, Kumar S, Richards JE, Kakon SH, Haque R, Petri WA, Lloyd-Fox S, Elwell C, Nelson CA, Using functional near-infrared spectroscopy to assess social information processing in poor urban Bangladeshi infants and toddlers., 2019; Developmental science. () e12839 PMID: 31017372 |

Turesky TK, Jensen SKG, Yu X, Kumar S, Wang Y, Sliva DD, Gagoski B, Sanfilippo J, Z?llei L, Boyd E, Haque R, Hafiz Kakon S, Islam N, Petri WA, Nelson CA, Gaab N, The relationship between biological and psychosocial risk factors and resting-state functional connectivity in 2-month-old Bangladeshi infants: a feasibility and pilot study., 2019; Developmental science. () e12841 PMID: 31016808 |

Saleh MM, Frisbee AL, Leslie JL, Buonomo EL, Cowardin CA, Ma JZ, Simpson ME, Scully KW, Abhyankar MM, Petri WA, Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection., 2019; Cell host & microbe. 25(5) 756-765.e5 PMID: 31003940 | PMCID: PMC6509008

Jensen SKG, Kumar S, Xie W, Tofail F, Haque R, Petri WA, Nelson CA, Neural correlates of early adversity among Bangladeshi infants., 2019; Scientific reports. 9(1) 3507 PMID: 30837491 | PMCID: PMC6401115

Uchiyama R, Kupkova K, Shetty SJ, Linford AS, Pray-Grant MG, Wagar LE, Davis MM, Haque R, Gaultier A, Mayo MW, Grant PA, Petri WA, Bekiranov S, Auble DT, Histone H3 lysine 4 methylation signature associated with human undernutrition., 2018; Proceedings of the National Academy of Sciences of the United States of America. 115(48) E11264-E11273 PMID: 30420518 | PMCID: PMC6275549

Kulaylat AS, Buonomo EL, Scully KW, Hollenbeak CS, Cook H, Petri WA, Stewart DB, Development and Validation of a Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection., 2018; JAMA surgery. () PMID: 30208386 |

Donowitz JR, Cook H, Alam M, Tofail F, Kabir M, Colgate ER, Carmolli MP, Kirkpatrick BD, Nelson CA, Ma JZ, Haque R, Petri WA, Role of maternal health and infant inflammation in nutritional and neurodevelopmental outcomes of two-year-old Bangladeshi children., 2018; PLoS neglected tropical diseases. 12(5) e0006363 PMID: 29813057 | PMCID: PMC5993301

Mahfuz M, Alam MA, Fahim SM, Gazi MA, Raihan MJ, Hossain M, Egner PA, Bessong PO, Petri WA, Groopman JD, Ahmed T, Aflatoxin exposure in children living in Mirpur, Dhaka: data from MAL-ED companion study., 2018; Journal of exposure science & environmental epidemiology. () PMID: 30185944 |

Sinha A, Kanungo S, Kim DR, Manna B, Song M, Park JY, Haldar B, Sharma P, Mallick AH, Kim SA, Babji S, Sur D, Kang G, Ali M, Petri WA, Wierzba TF, Czerkinsky C, Nandy RK, Dey A, Antibody secreting B cells and plasma antibody response to rotavirus vaccination in infants from Kolkata India., 2018; Heliyon. 4(1) e00519 PMID: 29560435 | PMCID: PMC5857522

Kumar M, Ji B, Babaei P, Das P, Lappa D, Ramakrishnan G, Fox TE, Haque R, Petri WA, B?ckhed F, Nielsen J, Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling., 2018; Metabolic engineering. 49() 128-142 PMID: 30075203 |

Mychaleckyj JC, Nayak U, Colgate ER, Zhang D, Carstensen T, Ahmed S, Ahmed T, Mentzer AJ, Alam M, Kirkpatrick BD, Haque R, Faruque ASG, Petri WA, Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient., 2018; Journal of medical genetics. 55(7) 459-468 PMID: 29514873 | PMCID: PMC6047159

Jiang NM, Cowan M, Moonah SN, Petri WA, The Impact of Systemic Inflammation on Neurodevelopment., 2018; Trends in molecular medicine. 24(9) 794-804 PMID: 30006148 | PMCID: PMC6110951

Lee B, Carmolli M, Dickson DM, Colgate ER, Diehl SA, Uddin MI, Islam S, Hossain M, Rafique TA, Bhuiyan TR, Alam M, Nayak U, Mychaleckyj JC, McNeal MM, Petri WA, Qadri F, Haque R, Kirkpatrick BD, Rotavirus-Specific Immunoglobulin A Responses Are Impaired and Serve as a Suboptimal Correlate of Protection Among Infants in Bangladesh., 2018; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67(2) 186-192 PMID: 29394355 | PMCID: PMC6030840

Schnee AE, Haque R, Taniuchi M, Uddin MJ, Petri WA, Evaluation of Two New Membrane-Based and Microtiter Plate Enzyme-Linked Immunosorbent Assays for Detection of Campylobacter jejuni in Stools of Bangladeshi Children., 2018; Journal of clinical microbiology. 56(9) PMID: 29925645 | PMCID: PMC6113481

Marie C, Ali A, Chandwe K, Petri WA, Kelly P, Pathophysiology of environmental enteric dysfunction and its impact on oral vaccine efficacy., 2018; Mucosal immunology. () PMID: 29988114 |

Duggal P, Petri WA, Does Malnutrition Have a Genetic Component?, 2018; Annual review of genomics and human genetics. 19() 247-262 PMID: 29874104 |

Troeger C, Khalil IA, Rao PC, Cao S, Blacker BF, Ahmed T, Armah G, Bines JE, Brewer TG, Colombara DV, Kang G, Kirkpatrick BD, Kirkwood CD, Mwenda JM, Parashar UD, Petri WA, Riddle MS, Steele AD, Thompson RL, Walson JL, Sanders JW, Mokdad AH, Murra..., Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years., 2018; JAMA pediatrics. 172(10) 958-965 PMID: 30105384 | PMCID: PMC6233802

Troeger C, Colombara DV, Rao PC, Khalil IA, Brown A, Brewer TG, Guerrant RL, Houpt ER, Kotloff KL, Misra K, Petri WA, Platts-Mills J, Riddle MS, Swartz SJ, Forouzanfar MH, Reiner RC, Hay SI, Mokdad AH, Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years., 2018; The Lancet. Global health. 6(3) e255-e269 PMID: 29433665 | PMCID: PMC5861379

Khalil IA, Troeger C, Rao PC, Blacker BF, Brown A, Brewer TG, Colombara DV, De Hostos EL, Engmann C, Guerrant RL, Haque R, Houpt ER, Kang G, Korpe PS, Kotloff KL, Lima AAM, Petri WA, Platts-Mills JA, Shoultz DA, Forouzanfar MH, Hay SI, Reiner RC, ..., Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study., 2018; The Lancet. Global health. 6(7) e758-e768 PMID: 29903377 | PMCID: PMC6005120

Richard SA, McCormick BJJ, Seidman JC, Rasmussen Z, Kosek MN, Rogawski ET, Petri W, Bose A, Mduma E, Maciel BLL, Chandyo RK, Bhutta Z, Turab A, Bessong P, Mahfuz M, Caulfield LE, Relationships among Common Illness Symptoms and the Protective Effect of Breastfeeding in Early Childhood in MAL-ED: An Eight-Country Cohort Study., 2018; The American journal of tropical medicine and hygiene. 98(3) 904-912 PMID: 29380724 | PMCID: PMC5930868

Korpe PS, Valencia C, Haque R, Mahfuz M, McGrath M, Houpt E, Kosek M, McCormick BJJ, Penataro Yori P, Babji S, Kang G, Lang D, Gottlieb M, Samie A, Bessong P, Faruque ASG, Mduma E, Nshama R, Havt A, Lima IFN, Lima AAM, Bodhidatta L, Shreshtha A, P..., Epidemiology and Risk Factors for Cryptosporidiosis in Children From 8 Low-income Sites: Results From the MAL-ED Study., 2018; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67(11) 1660-1669 PMID: 29701852 | PMCID: PMC6233690

Rogawski ET, Platts-Mills JA, Colgate ER, Haque R, Zaman K, Petri WA, Kirkpatrick BD, Quantifying the Impact of Natural Immunity on Rotavirus Vaccine Efficacy Estimates: A Clinical Trial in Dhaka, Bangladesh (PROVIDE) and a Simulation Study., 2018; The Journal of infectious diseases. 217(6) 861-868 PMID: 29514306 | PMCID: PMC5853827

Gilmartin AA, Petri WA, Exploring the mechanism of amebic trogocytosis: the role of amebic lysosomes., 2018; Microbial cell (Graz, Austria). 5(1) 1-3 PMID: 29354646 | PMCID: PMC5772035

Gilchrist CA, Cotton JA, Burkey C, Arju T, Gilmartin A, Lin Y, Ahmed E, Steiner K, Alam M, Ahmed S, Robinson G, Zaman SU, Kabir M, Sanders M, Chalmers RM, Ahmed T, Ma JZ, Haque R, Faruque ASG, Berriman M, Petri WA, Genetic diversity of Cryptosporidium hominis in a Bangladeshi community as revealed by whole genome sequencing., 2018; The Journal of infectious diseases. () PMID: 29514308 | PMCID: PMC6009673

Lee B, Dickson DM, deCamp AC, Ross Colgate E, Diehl SA, Uddin MI, Sharmin S, Islam S, Bhuiyan TR, Alam M, Nayak U, Mychaleckyj JC, Taniuchi M, Petri WA, Haque R, Qadri F, Kirkpatrick BD, Histo-Blood Group Antigen Phenotype Determines Susceptibility to Genotype-Specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy., 2018; The Journal of infectious diseases. 217(9) 1399-1407 PMID: 29390150 | PMCID: PMC5894073

Cowan M, Petri WA, Microglia: Immune Regulators of Neurodevelopment., 2018; Frontiers in immunology. 9() 2576 PMID: 30464763 | PMCID: PMC6234957

Kabir M, Ahmed E, Hossain B, Alam M, Ahmed S, Taniuchi M, Gilchrist CA, Houpt ER, Faruque ASG, Petri WA, Haque R, Giardia/Cryptosporidium QUIK CHEK? Assay is more Specific than qPCR for Rapid Point-of-care Diagnosis of Cryptosporidiosis in Infants in Bangladesh., 2018; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. () PMID: 29718129 |

Wojcik GL, Marie C, Abhyankar MM, Yoshida N, Watanabe K, Mentzer AJ, Carstensen T, Mychaleckyj J, Kirkpatrick BD, Rich SS, Concannon P, Haque R, Tsokos GC, Petri WA, Duggal P, Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease., 2018; mBio. 9(5) PMID: 30228239 | PMCID: PMC6143743

Schnee AE, Haque R, Taniuchi M, Uddin J, Alam M, Liu J, Rogawski ET, Kirkpatrick B, Houpt ER, Petri WA, Platts-Mills JA, Identification of etiology-specific diarrhea associated with linear growth faltering in Bangladeshi infants., 2018; American journal of epidemiology. () PMID: 29767678 |

Korpe PS, Gilchrist C, Burkey C, Taniuchi M, Ahmed E, Madan V, Castillo R, Ahmed S, Arju T, Alam M, Kabir M, Ahmed T, Petri WA, Haque R, Faruque ASG, Duggal P, Case-Control Study of Cryptosporidium Transmission in Bangladeshi Households., 2018; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. () PMID: 30192924 | PMCID: PMC6424084

Watanabe K, Petri WA, Learning from the research on amebiasis and gut microbiome: Is stimulation by gut flora essential for effective neutrophil mediated protection from external pathogens?, 2018; Gut microbes. () 1-5 PMID: 30252579 |

Abhyankar MM, Orr MT, Lin S, Suraju MO, Simpson A, Blust M, Pham T, Guderian JA, Tomai MA, Elvecrog J, Pedersen K, Petri WA, Fox CB, Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica., 2018; NPJ vaccines. 3() 22 PMID: 29900011 | PMCID: PMC5988657

Kulaylat AS, Buonomo EL, Scully KW, Hollenbeak CS, Cook H, Petri WA, Stewart DB, Development and Validation of a Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection., 2018; JAMA surgery. () PMID: 30208386 |

Steiner KL, Ahmed S, Gilchrist CA, Burkey C, Cook H, Ma JZ, Korpe PS, Ahmed E, Alam M, Kabir M, Tofail F, Ahmed T, Haque R, Petri WA, Faruque ASG, Species of Cryptosporidia Causing Subclinical Infection Associated With Growth Faltering in Rural and Urban Bangladesh: A Birth Cohort Study., 2018; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67(9) 1347-1355 PMID: 29897482 | PMCID: PMC6186860

Schnee AE, Petri WA, Campylobacter jejuni and associated immune mechanisms: short-term effects and long-term implications for infants in low-income countries., 2017; Current opinion in infectious diseases. 30(3) 322-328 PMID: 28157786 | PMCID: PMC5560167

Abhyankar MM, Noor Z, Tomai MA, Elvecrog J, Fox CB, Petri WA, Nanoformulation of synergistic TLR ligands to enhance vaccination against Entamoeba histolytica., 2017; Vaccine. 35(6) 916-922 PMID: 28089548 | PMCID: PMC5301946

Platts-Mills JA, Taniuchi M, Uddin MJ, Sobuz SU, Mahfuz M, Gaffar SA, Mondal D, Hossain MI, Islam MM, Ahmed AS, Petri WA, Haque R, Houpt ER, Ahmed T, Association between enteropathogens and malnutrition in children aged 6-23 mo in Bangladesh: a case-control study., 2017; The American journal of clinical nutrition. 105(5) 1132-1138 PMID: 28381477 | PMCID: PMC5402031

Upfill-Brown A, Taniuchi M, Platts-Mills JA, Kirkpatrick B, Burgess SL, Oberste MS, Weldon W, Houpt E, Haque R, Zaman K, Petri WA, Non-Specific Effects of Oral Polio Vaccine on Diarrheal Burden and Etiology among Bangladeshi Infants., 2017; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. () PMID: 28444240 | PMCID: PMC5848225

Ngobeni R, Samie A, Moonah S, Watanabe K, Petri WA, Gilchrist C, Entamoeba Species in South Africa: Correlations With the Host Microbiome, Parasite Burdens, and First Description of Entamoeba bangladeshi Outside of Asia., 2017; The Journal of infectious diseases. () PMID: 29236996 | PMCID: PMC5853652

Burgess SL, Gilchrist CA, Lynn TC, Petri WA, Parasitic Protozoa and Interactions with the Host Intestinal Microbiota., 2017; Infection and immunity. 85(8) PMID: 28584161 | PMCID: PMC5520446

Noor Z, Watanabe K, Abhyankar MM, Burgess SL, Buonomo EL, Cowardin CA, Petri WA, Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis., 2017; mBio. 8(1) PMID: 28246365 | PMCID: PMC5347349

Gilmartin AA, Ralston KS, Petri WA, Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing., 2017; mBio. 8(4) PMID: 28851845 | PMCID: PMC5574710

Jiang NM, Tofail F, Ma JZ, Haque R, Kirkpatrick B, Nelson CA, Petri WA, Early Life Inflammation and Neurodevelopmental Outcome in Bangladeshi Infants Growing Up in Adversity., 2017; The American journal of tropical medicine and hygiene. 97(3) 974-979 PMID: 28722635 | PMCID: PMC5590603

Ali A, Zaman U, Mahmud S, Zahid GE, Kazi M, Petri WA, Bhutta Z, Zaidi A, Hughes MA, Impact of maternal respiratory infections on low birth weight - a community based longitudinal study in an urban setting in Pakistan., 2017; BMC pregnancy and childbirth. 17(1) 111 PMID: 28399895 | PMCID: PMC5387226

Zhang Y, Zhou J, Niu F, Donowitz JR, Haque R, Petri WA, Ma JZ, Characterizing early child growth patterns of height-for-age in an urban slum cohort of Bangladesh with functional principal component analysis., 2017; BMC pediatrics. 17(1) 84 PMID: 28327104 | PMCID: PMC5359797

Lu M, Zhou J, Naylor C, Kirkpatrick BD, Haque R, Petri WA, Ma JZ, Application of penalized linear regression methods to the selection of environmental enteropathy biomarkers., 2017; Biomarker research. 5() 9 PMID: 28293424 | PMCID: PMC5345248

Ramakrishnan G, Petri WA, Secondary Carnitine Deficiency in Environmental Enteric Dysfunction., 2017; EBioMedicine. 17() 9-10 PMID: 28254256 | PMCID: PMC5360577

Burgess SL, Petri WA, The Intestinal Bacterial Microbiome and E. histolytica Infection., 2016; Current tropical medicine reports. 3() 71-74 PMID: 27525214 | PMCID: PMC4967426

Watanabe K, Petri WA, Environmental Enteropathy: Elusive but Significant Subclinical Abnormalities in Developing Countries., 2016; EBioMedicine. 10() 25-32 PMID: 27495791 | PMCID: PMC5006727

Burgess SL, Saleh M, Cowardin CA, Buonomo E, Noor Z, Watanabe K, Abhyankar M, Lajoie S, Wills-Karp M, Petri WA, Role of Serum Amyloid A, Granulocyte-Macrophage Colony-Stimulating Factor, and Bone Marrow Granulocyte-Monocyte Precursor Expansion in Segmented Filamentous Bacterium-Mediated Protection from Entamoeba histolytica., 2016; Infection and immunity. 84(10) 2824-32 PMID: 27456830 | PMCID: PMC5038085

Verkerke H, Sobuz S, Ma JZ, Petri SE, Reichman D, Qadri F, Rahman M, Haque R, Petri WA, Malnutrition Is Associated with Protection from Rotavirus Diarrhea: Evidence from a Longitudinal Birth Cohort Study in Bangladesh., 2016; Journal of clinical microbiology. 54(10) 2568-74 PMID: 27510830 | PMCID: PMC5035411

Guerrant RL, Leite AM, Pinkerton R, Medeiros PH, Cavalcante PA, DeBoer M, Kosek M, Duggan C, Gewirtz A, Kagan JC, Gauthier AE, Swann J, Mayneris-Perxachs J, Bolick DT, Maier EA, Guedes MM, Moore SR, Petri WA, Havt A, Lima IF, Prata MM, Michaleckyj..., Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil., 2016; PloS one. 11(9) e0158772 PMID: 27690129 | PMCID: PMC5045163

Ramakrishnan G, Wright M, Alam M, Naylor C, Kabir M, Zerin A, Ferdous T, Pedersen K, Hennig BJ, Donowitz JR, Wegmuller R, Haque R, Petri WA, Herbein J, Gilchrist CA, Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia., 2016; Diagnostic microbiology and infectious disease. () PMID: 27916543 | PMCID: PMC5292284

Hossain MI, Haque R, Mondal D, Mahfuz M, Ahmed AS, Islam MM, Guerrant RL, Petri WA, Ahmed T, Undernutrition, Vitamin A and Iron Deficiency Are Associated with Impaired Intestinal Mucosal Permeability in Young Bangladeshi Children Assessed by Lactulose/Mannitol Test., 2016; PloS one. 11(12) e0164447 PMID: 27906964 | PMCID: PMC5132308

Steele SP, Melchor SJ, Petri WA, Tuft Cells: New Players in Colitis., 2016; Trends in molecular medicine. 22(11) 921-924 PMID: 27717671 | PMCID: PMC5159242

Fleece ME, Heptinstall J, Khan SS, Kabir M, Herbein J, Haque R, Petri WA, Evaluation of a Rapid Lateral Flow Point-of-Care Test for Detection of Cryptosporidium., 2016; The American journal of tropical medicine and hygiene. 95(4) 840-841 PMID: 27573629 | PMCID: PMC5062784

Cowardin CA, Buonomo EL, Saleh MM, Wilson MG, Burgess SL, Kuehne SA, Schwan C, Eichhoff AM, Koch-Nolte F, Lyras D, Aktories K, Minton NP, Petri WA, The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia., 2016; Nature microbiology. 1(8) 16108 PMID: 27573114 | PMCID: PMC5010011

Ramakrishnan G, Pedersen K, Guenette D, Sink J, Haque R, Petri WA, Herbein J, Gilchrist CA, Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma., 2015; Diagnostic microbiology and infectious disease. () PMID: 25749462 |

Kirkpatrick BD, Colgate ER, Mychaleckyj JC, Haque R, Dickson DM, Carmolli MP, Nayak U, Taniuchi M, Naylor C, Qadri F, Ma JZ, Alam M, Walsh MC, Diehl SA, Petri WA, The "Performance of Rotavirus and Oral Polio Vaccines in Developing Countries" (PROVIDE) study: description of methods of an interventional study designed to explore complex biologic problems., 2015; The American journal of tropical medicine and hygiene. 92(4) 744-51 PMID: 25711607 | PMCID: PMC4385767

Gilchrist CA, Turner SD, Riley MF, Petri WA, Hewlett EL, Whole-genome sequencing in outbreak analysis., 2015; Clinical microbiology reviews. 28(3) 541-63 PMID: 25876885 | PMCID: PMC4399107

Watanabe K, Petri WA, Molecular biology research to benefit patients with Entamoeba histolytica infection., 2015; Molecular microbiology. () PMID: 26173474 |

Buonomo EL, Petri WA, The Bug Stops Here: Innate Lymphoid Cells in Clostridium difficile Infection., 2015; Cell host & microbe. 18(1) 5-6 PMID: 26159713 |

Gilmartin AA, Petri WA, Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response., 2015; Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 370(1671) PMID: 25964455 | PMCID: PMC4527388

Madan R, Petri WA, Role of obesity and adipose tissue-derived cytokine leptin during Clostridium difficile infection., 2015; Anaerobe. 34() 182-6 PMID: 25638400 | PMCID: PMC4492854

Petri WA, Naylor C, Haque R, Environmental enteropathy and malnutrition: do we know enough to intervene?, 2015; BMC medicine. 12() 187 PMID: 25604120 | PMCID: PMC4197320

Subramanian S, Huq S, Yatsunenko T, Haque R, Mahfuz M, Alam MA, Benezra A, DeStefano J, Meier MF, Muegge BD, Barratt MJ, VanArendonk LG, Zhang Q, Province MA, Petri WA, Ahmed T, Gordon JI, Persistent gut microbiota immaturity in malnourished Bangladeshi children., 2014; Nature. 510(7505) 417-21 PMID: 24896187 | PMCID: PMC4189846

Linford AS, Jiang NM, Edwards TE, Sherman NE, Van Voorhis WC, Stewart LJ, Myler PJ, Staker BL, Petri WA, Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase., 2014; Molecular and biochemical parasitology. () PMID: 24548880 | PMCID: PMC4022148

Moonah SN, Abhyankar MM, Haque R, Petri WA, The macrophage migration inhibitory factor homolog of Entamoeba histolytica binds to and immunomodulates host macrophages., 2014; Infection and immunity. 82(9) 3523-30 PMID: 24818664 | PMCID: PMC4187827

Jiang NM, Tofail F, Moonah SN, Scharf RJ, Taniuchi M, Ma JZ, Hamadani JD, Gurley ES, Houpt ER, Azziz-Baumgartner E, Haque R, Petri WA, Febrile illness and pro-inflammatory cytokines are associated with lower neurodevelopmental scores in Bangladeshi infants living in poverty., 2014; BMC pediatrics. 14() 50 PMID: 24548288 | PMCID: PMC3936797

Verkerke H, Naylor C, Zabeau L, Tavernier J, Petri WA, Marie C, Kinetics of leptin binding to the Q223R leptin receptor., 2014; PloS one. 9(4) e94843 PMID: 24743494 | PMCID: PMC3990580

Ralston KS, Solga MD, Mackey-Lawrence NM, Bhattacharya A, Petri WA, Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion., 2014; Nature. () PMID: 24717428 |

Gurley ES, Salje H, Homaira N, Ram PK, Haque R, Petri WA, Bresee J, Moss WJ, Luby SP, Breysse P, Azziz-Baumgartner E, Indoor exposure to particulate matter and age at first acute lower respiratory infection in a low-income urban community in bangladesh., 2014; American journal of epidemiology. 179(8) 967-73 PMID: 24607596 |

Checkley W, White AC, Jaganath D, Arrowood MJ, Chalmers RM, Chen X, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, X..., A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium., 2014; The Lancet. Infectious diseases. 15(1) 85-94 PMID: 25278220 | PMCID: PMC4401121

Moss DM, Priest JW, Hamlin K, Derado G, Herbein J, Petri WA, Lammie PJ, Longitudinal evaluation of enteric protozoa in haitian children by stool exam and multiplex serologic assay., 2014; The American journal of tropical medicine and hygiene. 90(4) 653-60 PMID: 24591430 |

Liu J, Lurain K, Sobuz SU, Begum S, Kumburu H, Gratz J, Kibiki G, Toney D, Gautam R, Bowen MD, Petri WA, Haque R, Houpt ER, Molecular genotyping and quantitation assay for rotavirus surveillance., 2014; Journal of virological methods. 213() 157-163 PMID: 25526999 |

Naylor C, Burgess S, Madan R, Buonomo E, Razzaq K, Ralston K, Petri WA, Leptin Receptor Mutation Results in Defective Neutrophil Recruitment to the Colon during Entamoeba histolytica Infection., 2014; mBio. 5(6) PMID: 25516614 | PMCID: PMC4271549

Donowitz JR, Petri WA, Pediatric small intestine bacterial overgrowth in low-income countries., 2014; Trends in molecular medicine. 21(1) 6-15 PMID: 25486880 |

Verkerke HP, Hanbury B, Siddique A, Samie A, Haque R, Herbein J, Petri WA, Multi-site clinical evaluation of a rapid test for Entamoeba histolytica in stool., 2014; Journal of clinical microbiology. () PMID: 25428152 |

Taniuchi M, Begum S, Uddin MJ, Platts-Mills JA, Liu J, Kirkpatrick BD, Chowdhury AH, Jamil KM, Haque R, Petri WA, Houpt ER, Kinetics of Poliovirus Shedding following Oral Vaccination as Measured by Quantitative Reverse Transcription-PCR versus Culture., 2014; Journal of clinical microbiology. 53(1) 206-11 PMID: 25378579 | PMCID: PMC4290924

Burgess SL, Buonomo E, Carey M, Cowardin C, Naylor C, Noor Z, Wills-Karp M, Petri WA, Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis., 2014; mBio. 5(6) e01817 PMID: 25370489 | PMCID: PMC4222101

Ahmed T, Mahfuz M, Islam MM, Mondal D, Hossain MI, Ahmed AS, Tofail F, Gaffar SA, Haque R, Guerrant RL, Petri WA, The MAL-ED cohort study in Mirpur, Bangladesh., 2014; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 59() S280-6 PMID: 25305298 |

Hsiao A, Ahmed AM, Subramanian S, Griffin NW, Drewry LL, Petri WA, Haque R, Ahmed T, Gordon JI, Members of the human gut microbiota involved in recovery from Vibrio cholerae infection., 2014; Nature. 515(7527) 423-6 PMID: 25231861 |

Cowardin CA, Petri WA, Host recognition of Clostridium difficile and the innate immune response., 2014; Anaerobe. 30() 205-9 PMID: 25223264 | PMCID: PMC4258135

Verkerke HP, Sobuz SU, Petri WA, Molecular diagnosis of infectious diarrhea: focus on enteric protozoa., 2014; Expert review of molecular diagnostics. 14(8) 935-46 PMID: 25139776 |